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Peptides for longevity & anti-aging

Compounds studied in the context of cellular aging, mitochondrial function and lifespan pathways. 25 compounds tracked in this category, ranked by community report volume — each with an evidence grade and links to the research.

COA-verified rankings 209 suppliers reviewed Rankings never sold — how we test
Longevity · 2.5 mg

FOXO4-DRI is a synthetic senolytic peptide that selectively kills off senescent 'zombie' cells by separating FOXO4 from p53. The result is r…

Longevity · 10 mg

Epitalon is a synthetic tetrapeptide that may activate telomerase to lengthen telomeres and extend cell lifespan. Created by Vladimir Khavin…

Longevity · 0.5-1 mg

Melanotan 1 is a synthetic alpha-MSH analog that stimulates melanin to darken skin without sun, is FDA-approved for certain conditions, and …

SS-31 A
Energy · 5 mg

SS-31 (Elamipretide) is a mitochondria-targeted tetrapeptide that binds cardiolipin to reduce oxidative stress and support mitochondrial fun…

Recovery · 0.1 mg

A synthetic Ala-Asp-Glu tripeptide marketed to stimulate cartilage and connective-tissue regeneration by normalizing chondrocyte protein syn…

GHK-Cu A−
Recovery · 1-2 mg

A naturally occurring copper-bound tripeptide that aids wound healing, collagen synthesis, and skin rejuvenation, used topically for skin an…

GLP-1 A+
Weight Loss · 0.25 mg

A gut incretin hormone that raises insulin in a glucose-dependent way, lowers glucagon, increases fullness, and slows digestion, forming the…

Immunity · 10 mg

A thymus-extracted peptide complex studied largely in Russia and Eastern Europe as an immune regulator and potential anti-aging agent, with …

Weight Loss · 220 mg

Adiponectin is a fat-tissue hormone that regulates glucose, fat breakdown, and insulin sensitivity via AMPK activation, with anti-inflammato…

General · Topical Concentr…

Argireline (acetyl hexapeptide-8) is a SNAP-25-derived synthetic peptide marketed as a topical alternative to botox, working by dampening ne…

Weight Loss · 50-150 mg orally daily

An oral NNMT-inhibitor research compound studied in animals for fat loss and metabolic health. No human trials exist, so all use is experime…

Memory · 1.7 g

A4 Amyloid Beta (Aβ) is an APP-derived peptide fragment that accumulates as brain plaques in Alzheimer's disease. Its buildup is a primary p…

B7-33 C+
Longevity · 1-5 mg

B7-33 is a synthetic single-chain RXFP1 agonist derived from the B-chain of human gene-2 relaxin, designed to mimic relaxin's vasoprotective…

Recovery · 1-5 mg

Cardiogen is a bioregulatory tetrapeptide (Ala-Glu-Asp-Arg) aimed at cardiovascular support, said to stimulate fibroblast proliferation and …

Longevity · Standard Concent…

Decapeptide-12 is a synthetic oligopeptide that inhibits tyrosinase to reduce skin hyperpigmentation. It blocks excess melanin production wi…

GDF-11 B
Longevity · 4.5 mg

A TGF-beta superfamily protein and activin type II receptor ligand that negatively regulates erythropoiesis; once hyped as a rejuvenation fa…

GLOW C+
Recovery · 10 units (3.5 mg blend) SubQ daily

Fixed-ratio GHK-Cu + BPC-157 + TB-500 blend (70 mg) aimed at skin, hair and tissue repair.

Recovery · 200-600 mg IM/subQ, 1-3x/week

The body's master antioxidant, injected IM or subQ for antioxidant support, recovery, detox, and skin; reassuring safety reputation but limi…

Muscle · 1-4 IU daily

FDA-approved growth hormone used off-label for fat loss, lean mass, and anti-aging; dosed in IU and requires careful glucose monitoring.

Longevity · 30 μg

Human Relaxin-2 (recombinant serelaxin) is a peptide hormone acting through RXFP1 to drive systemic and renal vasodilation via nitric oxide …

Humanin A−
Longevity · HNG Analog

A 24-amino-acid mitochondrial-derived peptide that protects cells by blocking apoptosis via Bax and Bcl-2 and by lowering oxidative stress a…

MOTS-c C
Energy · 5-10 mg weekly

MOTS-c is a mitochondrial-derived peptide studied for metabolism, energy, and healthy aging. Most data are from animals, and human evidence …

NAD+ C+
Longevity · 50-100 mg subQ (250-1000 mg slow IV)

Cellular energy coenzyme injected subQ or by slow IV for energy, recovery, and longevity; strong biology but thin human evidence and a notab…

Energy · No validated human dose (~250 mcg-1 mg/day reported)

A preclinical ERR-agonist exercise mimetic studied only in mice. No human data or validated dose exists, so any use is purely experimental.

Weight Loss · 2 mg daily

Tesamorelin is an FDA-approved peptide that stimulates natural growth hormone release to shrink deep belly (visceral) fat. It needs daily in…

Where researchers buy

The same top-ranked, COA-checked suppliers apply across categories:

★ Top 3 picksOur highest-rated, most transparent labs — compared side by side
#1
Serum Research
Featured partnerAffiliated · disclosure
#2
BioChain USA
#3
Nootropics Depot
Score9.6/109.5/109.5/10
COA✓ Yes✓ Yes✓ Yes
CountryUSAUSAUSA
Why we rate itFull per-batch COAs on every product and competitive pricing, from our affiliated partner — labeled as such wherever it appears.Published per-batch COAs, third-party testing, and a risk-free guarantee from a US-only shipper.Operates at a global scale with a high degree of transparency, and earns praise for its customer support and logistics.
Check prices at Serum Research →Read review →Check prices at BioChain USA →Read review →Check prices at Nootropics Depot →Read review →

Educational information only — not medical advice and not an endorsement to use any compound. Evidence grades summarize published research; most compounds here are unapproved research chemicals sold for laboratory use and labelled "not for human consumption."