Ipamorelin Dosage & Reconstitution Guide
Research and educational use only — not medical advice, and not for human consumption. The figures below are summarized from public sources, product labeling, and community reports, and are not a prescription or a substitute for a qualified clinician.
Reconstitution
Ipamorelin ships as a freeze-dried (lyophilized) powder that has to be mixed with bacteriostatic water before use. Draw 2 mL of bacteriostatic water into a syringe and add it to a 10 mg vial, letting the stream run down the inside wall of the glass rather than blasting the powder directly. Swirl gently — never shake — until the solution is clear, then keep it refrigerated.
Worked example. 2 mL into a 10 mg vial gives a concentration of 5 mg/mL (5000 mcg/mL). A 200 mcg dose then works out to 0.04 mL = 4 units on a U-100 insulin syringe. Scale the water volume up or down to make your target dose land on an easy-to-read mark (1 unit = 0.01 mL).
- Wipe both vial stoppers (peptide and bacteriostatic water) with an alcohol swab and let them dry.
- Draw 2 mL of bacteriostatic water into a syringe.
- Inject it slowly against the inside wall of the peptide vial.
- Swirl gently until fully dissolved; do not shake.
- Label the vial with the contents, concentration, and date, and store it in the refrigerator.
Dosing schedule
| Phase | Dose | Volume | Insulin units (U-100) | Notes |
|---|---|---|---|---|
| Weeks 1–2 | 100 mcg | 0.02 mL | 2 units | twice daily |
| Weeks 3–4 | 200 mcg | 0.04 mL | 4 units | twice daily |
| Weeks 5+ | 300 mcg | 0.06 mL | 6 units | 2–3× daily as tolerated |
Timing & cycling
Fasted shots work best — 30+ minutes before food. Classic slots: morning, post-workout, and/or bedtime. If you only take one, take it at bedtime.
Cycle length. 8–12 weeks, then 4+ weeks off.
Storage & handling
Keep the lyophilized (unmixed) vial refrigerated at 2–8 °C (36–46 °F) in a dry, dark place — it tolerates short periods at room temperature during shipping. Once reconstituted, store it at 2–8 °C, never frozen, and use it within about 2–4 weeks (sooner if the solution turns cloudy or discolored). Swab the stopper before every draw and use a fresh needle each time.
Supplies you'll need
- Ipamorelin vials — about 4 for an 8-week run at the upper dose
- Bacteriostatic water — 2 mL per vial (a 10–30 mL multi-dose bottle covers several vials)
- U-100 insulin syringes (0.3–0.5 mL / 30–50 unit barrels are easiest to read) — roughly 112 for 8 weeks, plus spares
- Alcohol swabs — one per injection and one per vial draw
- Sharps container for safe needle disposal
Key points
- The most selective of the GH secretagogues — minimal cortisol/prolactin spillover at normal doses.
- Frequently paired 1:1 with Modified GRF (1-29) in the same syringe for a synergistic pulse.
- Hunger uptick is normal and usually settles within 2 weeks.
What to monitor
IGF-1 after 6–8 weeks if you want objective confirmation; watch fasting glucose on long runs.
Legal & prescription status
In the US it is not sold as a standard FDA-approved drug, but it has been available by prescription through compounding pharmacies and telehealth clinics. The versions sold on research-chemical sites are unapproved and labelled 'not for human consumption.' (Note: FDA guidance on which peptides compounding pharmacies may prepare has tightened — availability changes over time.)
References
This guide is for research and educational purposes only. It is not medical advice and does not describe a product approved for human use. Always consult a qualified healthcare professional before considering any peptide protocol.